Science commentary: What is involved in intracytoplasmic sperm injection?

Intracytoplasmic sperm injection (ICSI).

Intracytoplasmic Sperm Injection

Intracytoplasmic Sperm Injection (ICSI) is an assisted reproductive technique [4] (ART) initially developed by Dr. Gianpiero D. Palermo [5] in 1993 to treat male infertility [6]. It is most commonly used in conjunction with in vitro [7] fertilization [8] (IVF) or a less commonly used technique called zygote intrafallopian transfer [9] (ZIFT). In natural fertilization [8], the sperm [10] must pe...

Intracytoplasmic sperm injection: method and application in veterinary science

Intracytoplasmic sperm injection is the newest and the most successful micromanipulation technique for treating male factor infertility. It entails the mechanical insertion of a chosen spermatozoon directly in to the cytoplasm of an oocyte. The technique was used in veterinary science for the purpose of clarifying the different steps of fertilization by investigating the fusion and penetration ...

Intracytoplasmic sperm injection (ICSI)

IVF has become a well-established treatment for certain types of infertility, including long-standing infertility due to tubal disease, endometriosis, unexplained infertility or infertility involving a male factor. Soon it became clear that certain couples with severe male-factor infertility could not be helped by conventional IVF. Extremely low sperm counts, impaired motility and/or abnormal m...

Comparison between intracytoplasmic sperm injection and intracytoplasmic morphologically selected sperm injection in oligo-astheno-teratozoospermia patients

OBJECTIVE The aim of this study was to evaluate the efficiency of the intracytoplasmic morphologically selected sperm injection (IMSI) technique compared with conventional ICSI and previous ICSI attempts in oligo-astheno-teratozoospermia (OAT) patients. METHODS The sperms were selected under high magnification (6,600×) and used to induce fertilization in previous ICSI patients by IMSI. These ...